Setting the interpolation does not carry through to any images created by imageaffine() or imagerotate(). It defaults to IMG_BILINEAR_FIXED and would need to be set on each generated image as required.
<?php
imagesetinterpolation( $image, IMG_NEAREST_NEIGHBOUR );
// Rotated using IMG_NEAREST_NEIGHBOUR
$rotated = imagerotate( $image, 45, $transparent );
// Rotated using IMG_BILINEAR_FIXED
$rotated_again = imagerotate( $rotated, 45, $transparent );
?>
Setting the interpolation to IMG_NEAREST_NEIGHBOUR can help to preserve details and prevent sampling issues when rotating an image at 90 degree increments, including when rotating clockwise.
<?php
// Rotated image can appear blurred and on a slight angle.
$rotated = imagerotate( $image, -360, $transparent );
// Similar to starting Image although it may still show a background or be on a slight angle.
imagesetinterpolation( $image, IMG_NEAREST_NEIGHBOUR );
$rotated = imagerotate( $image, -360, $transparent );
?>